At the moment, there are two forms of research on itaconate: Irg1−/− macrophages and the regulatory outcome of itaconate derivatives. Both of these effects were being complementary and unveiled which the regulatory mechanisms of itaconate concerned alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription aspect 3 (ATF3) https://vistusertib88765.tkzblog.com/29622676/about-sr-18292