Pentobarbital will minimize the extent or impact of nisoldipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will minimize the extent or impact of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Watch patients previously on buprenorphine subdermal implant who requi... https://wilhelmp689rjz3.national-wiki.com/user